Androgenetic Alopecia

Androgenetic alopecia, also known as genetic baldness, is the main cause of both male and female hair loss.

It affects 50% of men by the age of 50 and up to 85% by the age of 70.

After menopause, up to 40% may be affected.

Androgenetic alopecia is an inherited condition whose first symptoms usually start after puberty.

Androgenetic alopecia has a gradual and variable evolution.

It seems to manifest itself differently in various races and people.

Caucasians tend to have the earliest and most intense presentation.

African Americans and Asians commonly have a milder presentation, including less chance to develop a receding hairline.

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    Causes of androgenetic alopecia

    The main causes of androgenetic alopecia are hormonal disturbances and genetics.

    There is scientific evidence of the contribution of environmental factors, but it is not clear the mechanisms by which they contribute to hair loss.

    It has been proposed that external factors are associated with earlier onset and faster progression.

    In this case, external factors such as stress increase free radicals, which lead to faster cellular aging.

    Free radicals are highly reactive compounds originated by oxidative stress, as a result of harm from internal or external agents.

    Free radicals react with cells and tissues, provoking damages which can change cellular functions.

    The cumulative damages lead to the cellular aging related to hair loss.



    Miniaturization is the process of hair thinning and shortening induced by the male hormone DHT.

    Usually, miniaturization is progressive. The hair shafts become thin or even absent, which characterizes the permanent hair loss.

    Psychological impact of androgenetic alopecia

    Hair is an essential part of self image, which directly interferes with social life.

    Therefore, the consequences of androgenetic alopecia are predominantly psychological.

    There are some studies showing the negative impacts on self-esteem and quality of life of those individuals.

    Anxiety and depression are common feelings associated with hair loss.

    Since adolescence is a transitional time of identity formation, teenagers are specially affected.

    The emotional impact of hair loss in women can be devastating.

    Relationships, work and even professional career can be affected by hair loss.

    Androgenetic alopecia

    Clinical features: differences between male and female baldness

    There are some different clinical aspects between male and female pattern hair loss.

    Contact Us

    Doppio Clinic has an appropriate infrastructure to evaluate and treat your hair loss. Doppio Clinic is headed by a hair loss specialist physician who leads a team of professionals prepared to help you with your hair problems.

    Make an appointment today to get the information and advice about your hair loss.

    +55 (11) 93801-1653

    +55 (11) 3853-9175

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    Av. Lavandisca, 777, 3º andar
    Moema, São Paulo - SP

    Associated medical conditions

    Scientific studies have suggested an association between androgenetic alopecia and health medical conditions.

    According to scientific data, people with baldness are likely to present hypertension, heart attack, diabetes, higher cholesterol levels, atherosclerosis and cancer.

    Men also have an additional risk of infertility, benign prostate enlargement, intestinal and prostate cancer.

    Androgenetic alopecia: treatment

    There are efficient therapies for prevention, control and recovery of hair loss in androgenetic alopecia.

    Since treatments are properly prescribed and executed, the results are excellent.

    In order to get the best treatment option, it is recommended to evaluate the hair loss degree and extension.

    Mild or moderate hair loss is often well responsive to medical devices, oral and topical medications.

    In cases of more advanced hair loss, scalp reconstruction is recommended.

    The scalp reconstruction may be performed with surgical hair transplantation or non-surgical hair replacement methods.

    The decision regarding the treatment depends on the correct diagnosis.

    Therefore, it is important to schedule a medical appointment as soon as you notice the first signs of hair loss.